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Bethyl Laboratories
HNRNPQ/R Polyclonal Antibody
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Product Details
A305-900A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A region between residue 573 and 623 of human Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (hnRNP-Q) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7.0 to 8.0
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Predicted reactivity by homology: Rat, Mouse.
Target Information
The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Glycine- and tyrosine-rich RNA-binding protein; GRY-RBP; Heterogeneous nuclear ribonucleoprotein Q; Heterogeneous nuclear ribonucleoprotein R; hnRNP Q; hnRNP R; hnRNP-R2; NS1-associated protein 1; RRM RNA binding protein; similar to Homo sapiens Hn RNP R; Synaptotagmin-binding, cytoplasmic RNA-interacting protein; unnamed protein product
Gene Aliases: GRY-RBP; GRYRBP; hnRNP-Q; hnRNP-R; HNRNPQ; HNRNPR; HNRPQ; HNRPQ1; HNRPR; NEDDFSB; NSAP1; PP68; SYNCRIP
UniProt ID: (Human) O43390, (Human) O60506
Entrez Gene ID: (Human) 10236, (Human) 10492
mRNA splicing, via spliceosome
mRNA processing
RNA splicing
osteoblast differentiation
RNA processing
regulation of translation
mRNA modification
negative regulation of translation
CRD-mediated mRNA stabilization
cellular response to interferon-gamma
chromosomal 5-methylcytosine DNA demethylation pathway
negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
positive regulation of cytoplasmic translation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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