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Abnova
HNRNPU Monoclonal Antibody (4G11)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00003192-M03
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
4G11
抗原
HNRNPU (NP_004492.2, 352 a.a. approximately 460 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: LLGEEEFSYG YSLKGIKTCN CETEDYGEKF DENDVITCFA NFESDEVELS YAKNGQDLGV AFKISKEVLA GRPLFPHVLC HNCAVEFNFG QKEKPYFPIP EEYTFIQNV
靶标信息
The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: contains signal peptide domain; FLJ30202; FLJ37978; heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A); heterogenous nuclear ribonucleoprotein U; HNRNPU antisense RNA 1; NCRNA00201; nuclear matrix protein sp120; nuclear p120 ribonucleoprotein; p120 nuclear protein; SAR-DNA binding protein of the nuclear scaffold; scaffold attachment factor A; U211; unnamed protein product
基因别名: DEE54; EIEE54; GRIP120; hnRNP U; HNRNPU-AS1; HNRPU; pp120; SAF-A; SAFA; Sp120; U21.1
UniProt ID: (Human) Q00839, (Mouse) Q8VEK3
Entrez Gene ID: (Human) 3192, (Mouse) 51810
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core binding
TFIIH-class transcription factor binding
DNA binding
chromatin binding
double-stranded DNA binding
single-stranded DNA binding
transcription corepressor activity
RNA binding
double-stranded RNA binding
single-stranded RNA binding
mRNA 3'-UTR binding
actin binding
protein binding
ATP binding
poly(A) binding
snRNA binding
poly(C) RNA binding
chromatin DNA binding
poly(G) binding
piRNA binding
pre-mRNA binding
identical protein binding
ribonucleoprotein complex binding
sequence-specific DNA binding
macromolecular complex binding
telomerase RNA binding
RNA polymerase II C-terminal domain binding
lncRNA binding
sequence-specific double-stranded DNA binding
promoter-specific chromatin binding
negative regulation of transcription from RNA polymerase II promoter
alternative mRNA splicing, via spliceosome
regulation of alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
osteoblast differentiation
chromatin organization
RNA processing
regulation of mitotic cell cycle
dosage compensation by inactivation of X chromosome
regulation of gene expression
chromatin silencing by small RNA
negative regulation of telomere maintenance via telomerase
circadian regulation of gene expression
negative regulation of kinase activity
negative regulation of transcription elongation from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
mRNA stabilization
maintenance of protein location in nucleus
random inactivation of X chromosome
CRD-mediated mRNA stabilization
cellular response to glucocorticoid stimulus
positive regulation of brown fat cell differentiation
dendritic transport of messenger ribonucleoprotein complex
negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
regulation of mitotic spindle assembly
regulation of chromatin organization
positive regulation of attachment of mitotic spindle microtubules to kinetochore
protein localization to spindle microtubule
RNA localization to chromatin
cellular response to leukemia inhibitory factor
adaptive thermogenesis
positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
positive regulation of stem cell proliferation
negative regulation of stem cell differentiation
positive regulation of cytoplasmic translation
positive regulation of gene expression
mRNA metabolic process
erythrocyte differentiation
cardiac muscle cell development
cellular response to dexamethasone stimulus
Disclaimer
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