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Invitrogen
HOMER3 Polyclonal Antibody
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产品信息
PA5-59383
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
C. elegans,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.30 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ALVQTKDQEI QTLKSQTGGP REALEAAERE ETQQKVQDLE TRNAELEHQL RAMERSLEEA RAERERARAE VGRAAQLLDV RLFELSELRE GL
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 88%.
靶标信息
This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: homer homolog 3; Homer protein homolog 3; Homer, neuronal immediate early gene, 3; Homer-3
基因别名: HOMER-3; HOMER3; VESL3
UniProt ID: (Human) Q9NSC5
Entrez Gene ID: (Human) 9454
