Invitrogen

HOXB4 Recombinant Rabbit Monoclonal Antibody (23GB6620)

Name: HOXB4 Recombinant Rabbit Monoclonal Antibody (23GB6620)
Brand: Invitrogen
SKU: MA5-53078

查看其他8个HOXB4抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

图: 1 / 1

HOXB4 Antibody (MA5-53078) in WB

Western Blot analysis of HOXB4. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with HOXB4 recombinant monoclonal antibody (Product # MA5-53078) with a dilution of 1:5,000, followed by HRP-conjugated goat anti-rabbit secondary antibody with a dilution of 1:20,000. Image was developed using FeQTM ECL Substrate Kit.

Product Image Gallery

Immunogen image

Immunogen Image HOXB4 Recombinant Rabbit Monoclonal Antibody (23GB6620)

产品信息

MA5-53078

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:5,000

产品规格

种属反应

Human, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293F

分类

Recombinant Monoclonal

类型

Antibody

克隆号

23GB6620

抗原

A synthesized peptide derived from human HOXB4 (21-55AA).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_3249553

靶标信息

HOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation. HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs. Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype. Activation of WNT signaling in HSCs induced increased expression of HOXB4. Perturbations of HOX gene expression can cause leukemia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。