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Invitrogen
HOXB5 Polyclonal Antibody
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产品信息
PA5-35898
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human HOXB5. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Recommended positive controls: HepG2 WCE and NE.
Predicted reactivity: Mouse (97%), Rat (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxB5 (homeobox protein Hox-B5), also known as HOX2, HU-1, HOX2A, Hox2.1 or HHO.C10, is a member of the Antp homeobox (Hox) family. It is a 269 amino acid long nuclear protein expressed in the central nervous system. HoxB5 contains one homeobox DNAbinding domain and plays a role in the regulation of lung and gut development, providing cells with positional identities on the anterior-posterior body axis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: homeo box 2A; homeo box B5; Homeobox protein HHO.C10; Homeobox protein Hox-2A; Homeobox protein Hox-B5; Homeobox protein Hu-1
基因别名: HHO.C10; HOX2; Hox2.1; HOX2A; HOXB5; HU-1
UniProt ID: (Human) P09067
Entrez Gene ID: (Human) 3215
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
