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Invitrogen
HSD17B3 Polyclonal Antibody
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HSD17B3 Antibody (PA5-143917) in WB
Western blot analysis of HSD17B3 using HSD17B3 antibody (Product # PA5-143917). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. Lane 1: human U20S whole cell lysates; Lane 2: human HEL whole cell lysates; Lane 3: rat testis tissue lysates; Lane 4: rat liver tissue lysates; Lane 5: mouse liver tissue lysates; Lane 6: mouse RAW264. 7 whole cell lysates. After electrophoresis, proteins were t... View More
产品信息
PA5-143917
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence of human HSD17B3 (NLLPSHFLNAPDEIQSLIH).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human U20S whole cell, human HEL whole cell, rat testis tissue, rat liver tissue, mouse liver tissue, mouse RAW2647 whole cell. Flow: HepG2 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 17(beta)HSD type 3; 17-beta-HSD 3; 17-beta-HSD3; 17-beta-hydroxysteroid dehydrogenase type 3; 17beta-HSD; estradiol 17 beta-dehydrogenase 3; Estradiol 17-beta-dehydrogenase 2; hydroxysteroid (17-beta) dehydrogenase 3; hydroxysteroid dehydrogenase 3; Short chain dehydrogenase/reductase family 12C member 2; short chain dehydrogenase/reductase family 12C, member 2; Testicular 17-beta-hydroxysteroid dehydrogenase; Testosterone 17-beta-dehydrogenase 3
基因别名: EDH17B3; HSD17B3; SDR12C2
UniProt ID: (Human) P37058, (Mouse) P70385, (Rat) O54939
Entrez Gene ID: (Human) 3293, (Mouse) 15487, (Rat) 117182
lipid metabolic process
steroid biosynthetic process
metabolic process
oxidation-reduction process
organic acid metabolic process
response to herbicide
response to metal ion
response to lead ion
response to organic cyclic compound
response to activity
response to insecticide
insecticide metabolic process
biphenyl metabolic process
phenol-containing compound metabolic process
hippocampus development
response to nutrient levels
cellular response to hormone stimulus
response to vitamin E
Leydig cell differentiation
response to L-ascorbic acid
response to estrogen
response to ethanol
response to arsenic-containing substance
response to cadmium ion
response to steroid hormone
response to corticosterone
response to fungicide
testosterone biosynthetic process
response to fatty acid
cellular response to antibiotic
cellular response to gonadotropin stimulus
androgen biosynthetic process
male genitalia development
