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Invitrogen
HSD17B4 Monoclonal Antibody (OTI1F3)
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产品信息
MA5-26306
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI1F3
抗原
Full length human recombinant protein of HSD17B4 produced in HEK293T cell
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Peroxisomal multifunctional enzyme type 2 is a protein that in humans is encoded by the HSD17B4 gene. The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 17-beta-HSD 4; 17-beta-HSD IV; 17-beta-hydroxysteroid dehydrogenase 4; 17beta-estradiol dehydrogenase type IV; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; beta-hydroxyacyl dehydrogenase; beta-keto-reductase; D-3-hydroxyacyl-CoA dehydratase; D-bifunctional protein; D-bifunctional protein, peroxisomal; DBP; hydroxysteroid (17-beta) dehydrogenase 4; hydroxysteroid dehydrogenase 4; MFE-2; MFP-2; Multifunctional protein 2; Peroxisomal multifunctional enzyme type 2; peroxisomal multifunctional protein 2; Short chain dehydrogenase/reductase family 8C member 1; short chain dehydrogenase/reductase family 8C, member 1
基因别名: DBP; EDH17B4; HSD17B4; MFE-2; MPF-2; PRLTS1; SDR8C1
UniProt ID: (Human) P51659
Entrez Gene ID: (Human) 3295
very long-chain fatty acid metabolic process
osteoblast differentiation
fatty acid beta-oxidation
bile acid biosynthetic process
androgen metabolic process
estrogen metabolic process
fatty acid beta-oxidation using acyl-CoA oxidase
alpha-linolenic acid metabolic process
very long-chain fatty-acyl-CoA metabolic process
medium-chain fatty-acyl-CoA metabolic process
Sertoli cell development
