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Invitrogen
HSPA14 Polyclonal Antibody
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产品信息
PA5-61173
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: FTVLFPSGTP LPARRQHTLQ APGSISSVCL ELYESDGKNS AKEETKFAQV VLQDLDKKEN GLRDILAVLT MKRDGSLHVT CTDQETGKCE AIS
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 96%.
靶标信息
The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1 beta, TNF alpha, and the chemokines IP-10, MIP-1 alpha, MIP-1 beta and normal T cell expressed and secreted (RANTES).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Heat shock 70 kDa protein 14; heat shock 70kDa protein 14 isoform 1 variant 3; Heat shock protein; Heat shock protein family A member 14; Heat shock protein HSP60; heat shock protein hsp70-related protein; HSP; HSP70-like protein 1; HSP7E
基因别名: HSP60; HSP70-4; HSP70L1; HSPA14
UniProt ID: (Human) Q0VDF9
Entrez Gene ID: (Human) 51182
