Search
Invitrogen
HSPA9 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-79409
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Grp75 (591-609aa DTETKMEEFKDQLPADECN).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human A549 whole cell, human Jurkat whole cell, human HepG2 whole cell, rat testis tissue, mouse testis tissue, mouse NIH/3T3 whole cell. IHC: human lung cancer tissue, rat liver tissue IHC-F: rat liver tissue. ICC/IF: A549 cell.
Target Information
The HSP70 family is composed of four highly conserved proteins: HSP70, HSC70, GRP75 and GRP78. These proteins serve a variety of roles. GRP75 expression is restricted to the mitochondrial matrix and aids in the translocation and folding of nascent polypeptide chains of both nuclear and mitochondrial origin. GRP75 and GRP78 are unresponsive to heat stress and are induced by glucose deprivation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 70 kda heat shock protein precursor; 75 kDa glucose-regulated protein; C3H-specific antigen; catecholamine regulated protein 40; catecholamine-regulated protein 40; CRP40; epididymis secretory sperm binding protein Li 124m; GRP 75; GRP-75; heat shock 70 kDa protein 9; heat shock 70kD protein 9B; heat shock 70kDa protein 9 (mortalin); heat shock 70kDa protein 9A; Heat shock protein; heat shock protein 9; heat shock protein 9A; heat shock protein cognate 74; heat shock protein family A member 9; heat shock protein, 74 kDa, A; heat shock protein, A; HSP; MGC4500; mortalin; mortalin, perinuclear; mortalin-2; mortalin2; mtHSP70; p66 MOT; p66-mortalin; peptide-binding protein 74; stress-70 protein, mitochondrial-like; unnamed protein product
Gene Aliases: 74kDa; CRP40; CSA; EVPLS; GRP-75; GRP75; HEL-S-124m; Hsc74; Hsp74; Hsp74a; Hspa9a; HSPA9B; Mortalin; MOT; Mot-2; MOT2; Mthsp70; MTHSP75; PBP74; SAAN; SIDBA4
UniProt ID: (Human) P38646, (Mouse) P38647, (Rat) P48721
Entrez Gene ID: (Human) 3313, (Mouse) 15526, (Rat) 291671
protein folding
protein export from nucleus
response to toxic substance
iron-sulfur cluster assembly
erythrocyte differentiation
calcium ion transmembrane import into mitochondrion
protein refolding
positive regulation of apoptotic process
regulation of erythrocyte differentiation
negative regulation of erythrocyte differentiation
protein autophosphorylation
response to folic acid
cellular response to interleukin-1
response to thyroxine
negative regulation of hematopoietic stem cell differentiation
negative regulation of hemopoiesis
intracellular protein transport
inner mitochondrial membrane organization
protein import into mitochondrial matrix
negative regulation of apoptotic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support