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Invitrogen
HTLV-2 env 801 Monoclonal Antibody (8.A.033)
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产品信息
MA1-91454
产品规格
种属反应
Virus
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
8.A.033
抗原
Highly purified HTLV-II envelope 801 antigen.
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Protein G
保存液
0.1M tris HCl, pH 7.5
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA1-91454 detects HTLV2 env 801 from human samples.
靶标信息
The HTLV-2 env 801 gene encodes the envelope glycoprotein, which is pivotal for virus entry into host cells. Human T-cell leukemia virus type 2 (HTLV-2) shares many structural features with HTLV-1, with the envelope (Env) protein being a critical component in mediating viral entry via interaction with cell surface receptors. The env gene product is synthesized as a precursor that is cleaved into the surface (SU) and transmembrane (TM) subunits. The SU subunit facilitates receptor binding, while the TM subunit aids in membrane fusion, enabling the virus to enter the host cell. HTLV-2 predominantly targets and transforms CD8+ T-cells, distinct from HTLV-1, which primarily transforms CD4+ T-cells. Understanding the structural and functional nuances of the HTLV-2 envelope protein is crucial as it presents a target for therapeutic interventions aimed at preventing viral entry and subsequent infection.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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