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Invitrogen
HTR1A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-75267
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 291-340 of Human HTR1A.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 5-HT-1A; 5-HT1A; 5-HT1A receptor; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled; 5-hydroxytryptamine receptor; G-protein coupled receptor 18; guanine nucleotide-binding regulatory protein-coupled receptor; serotonin 1A receptor; serotonin 5-HT1A receptor; serotonin receptor; serotonin receptor 1A; unnamed protein product
基因别名: 5-HT-1A; 5-HT1A; 5HT1A; ADRB2RL1; ADRBRL1; G-21; Gpcr18; PFMCD; RAT5HT1A
UniProt ID: (Human) P08908, (Rat) P19327, (Mouse) Q64264
Entrez Gene ID: (Human) 3350, (Rat) 24473, (Mouse) 15550
behavioral fear response
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting serotonin receptor signaling pathway
serotonin receptor signaling pathway
gamma-aminobutyric acid signaling pathway
chemical synaptic transmission
negative regulation of gamma-aminobutyric acid secretion
regulation of serotonin secretion
regulation of vasoconstriction
positive regulation of microtubule depolymerization
behavioral response to nicotine
exploration behavior
regulation of dopamine metabolic process
serotonin metabolic process
response to morphine
regulation of hormone secretion
regulation of behavior
regulation of feeding behavior
vocalization behavior
NMDA glutamate receptor clustering
response to alcohol
presynaptic modulation of chemical synaptic transmission
response to glycoside
positive regulation of cell proliferation
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
