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Invitrogen
HTR1A Polyclonal Antibody
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HTR1A Antibody (PA5-95035) in IHC (P)
Immunohistochemistry (Paraffin) analysis of HTR1A in paraffin-embedded section of human endometrial adenocarcinoma tissue using HTR1A Polyclonal Antibody (Product # PA5-95035). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilut... View More
产品信息
PA5-95035
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT1A Receptor (404-422aa NKDFQNAFKKIIKCKFCRQ).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human hepatocellular carcinoma tumor tissue (HCCT), rat liver tissue. IHC: human endometrial adenocarcinoma tissue, human lung cancer tissue, rat lymphaden tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5-HT-1A; 5-HT1A; 5-HT1a receptor; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled; 5-hydroxytryptamine receptor 1A; G-21; guanine nucleotide-binding regulatory protein-coupled receptor; Serotonin receptor 1A
基因别名: 5-HT-1A; 5-HT1A; 5HT1A; ADRB2RL1; ADRBRL1; G-21; HTR1A; PFMCD; RAT5HT1A
UniProt ID: (Human) P08908, (Rat) P19327
Entrez Gene ID: (Human) 3350, (Rat) 24473
behavioral fear response
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting serotonin receptor signaling pathway
serotonin receptor signaling pathway
cell proliferation
positive regulation of cell proliferation
regulation of serotonin secretion
exploration behavior
regulation of dopamine metabolic process
vasoconstriction
serotonin metabolic process
regulation of hormone secretion
regulation of behavior
positive regulation of microtubule depolymerization
regulation of feeding behavior
NMDA glutamate receptor clustering
