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Invitrogen
HTR1E Polyclonal Antibody
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产品信息
PA5-33297
产品规格
种属反应
Bat,
Bovine,
Horse,
Guinea pig,
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human 5HT1E Receptor.
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Elephant, Bovine, Bat, Horse, Guinea pig (100%).
靶标信息
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5-HT-1E; 5-HT1E; 5-HT1e receptor; 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled; 5-hydroxytryptamine receptor 1E; 5HT1E Receptor; HT1e receptor; S31; Serotonin receptor 1E
基因别名: 5-HT1E; 5HT1E; HTR1E
UniProt ID: (Human) P28566, (Guinea pig) Q6VB83
Entrez Gene ID: (Human) 3354, (Horse) 100065574, (Bovine) 616356, (Guinea pig) 100379275
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
serotonin receptor signaling pathway
chemical synaptic transmission
negative regulation of cAMP metabolic process
