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Invitrogen
HUS1 Polyclonal Antibody
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产品信息
PA5-55417
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: NHFTRISNMI AKLAKTCTLR ISPDKLNFIL CDKLANGGVS MWCELEQENF FNEFQMEGVS AENNEIYLEL TSENLSRASK TAQNARALKI KLTNKHFPCL TVSVELLSMS SSSRIVTHD
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.
靶标信息
The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Checkpoint protein HUS1; hHUS1; HUS1 checkpoint homolog; HUS1 protein; hus1+-like protein
基因别名: hHUS1; HUS1
UniProt ID: (Human) O60921
Entrez Gene ID: (Human) 3364
DNA damage checkpoint
double-strand break repair via homologous recombination
regulation of protein phosphorylation
DNA replication
DNA repair
nucleotide-excision repair
protein phosphorylation
cellular response to DNA damage stimulus
negative regulation of DNA replication
response to UV
embryo development
intra-S DNA damage checkpoint
mitotic DNA replication checkpoint
meiotic DNA integrity checkpoint
cellular response to ionizing radiation
regulation of signal transduction by p53 class mediator
