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NeoBiotechnologies
Heart Fatty Acid Binding Protein (H-FABP)/FABP3 Monoclonal Antibody (FABP3/3770)
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Heart Fatty Acid Binding Protein (H-FABP)/FABP3 Antibody (2170-MSM4-P1) in IHC (P)
Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human heart stained with FABP3 Mouse Monoclonal Antibody (FABP3/3770). Inset: PBS instead of primary antibody; secondary only negative control.
产品信息
2170-MSM4-P1
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
FABP3/3770
抗原
Human recombinant FABP3 protein fragment (around aa 1-127) (exact sequence is proprietary).
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein G
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Fatty acid binding proteins (FABP) are small (approximately 13-14 kDa) intracellular proteins with a high degree of tissue specificity. FABPs are a class of cytoplasmic proteins that bind long chain fatty acids. They are abundantly present in various cell types and seem to play an important role in the intracellular utilization of fatty acids. There are at least six distinct types of FABP, each showing a specific pattern of tissue expression. FABP leaks, due to its small size, rapidly out of is chemically damaged dying cells leading to a rise in serum levels. Liver FABP is a sensitive marker for cell damage of liver cells in vitro and in vivo. Is chemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. Next to this L FABP is a marker for rapid hepatocyte lysis in vitro (as for example in toxicology assays) and for detection of liver damage during and after transplantation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 422 protein; Cardiac Fatty Acid Binding Protein; FABP 3; fatty acid binding protein 11; Fatty acid binding protein 11 (FABP11); fatty acid binding protein 3, muscle and heart; Fatty acid binding protein heart; Fatty acid-binding protein 3; Fatty acid-binding protein, heart; H-FABP; heart FABP; Heart type fatty acid binding protein; Heart-type fatty acid-binding protein; M FABP; M-FABP; Mammary derived growth inhibitor; Mammary-derived growth inhibitor; MDGI; muscle and heart (mammary derived growth inhibitor); Muscle fatty acid binding protein; Muscle fatty acid-binding protein; Muscle O-FABP; Mylein protein P2 homolog / adopocyte
基因别名: FABP11; FABP3; H-FABP; M-FABP; MDGI; O-FABP
UniProt ID: (Human) P05413
Entrez Gene ID: (Human) 2170
fatty acid metabolic process
negative regulation of cell proliferation
long-chain fatty acid transport
triglyceride catabolic process
response to insulin
response to drug
cholesterol homeostasis
long-chain fatty acid import
regulation of fatty acid oxidation
phospholipid homeostasis
response to fatty acid
positive regulation of phospholipid biosynthetic process
