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Invitrogen
Heparin Cofactor II Polyclonal Antibody
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Heparin Cofactor II Antibody (PA5-110356) in WB
Western blot analysis of Heparin Cofactor II in extracts of various cell lines. Samples were incubated with Heparin Cofactor II Polyclonal antibody (Product # PA5-110356) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-110356
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 20-290 of human SERPIND1 (NP_000176.2).
偶联物
形式
Liquid
浓度
0.22 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GSKGPLDQLE KGGETAQSAD PQWEQLNNKN LSMPLLPADF HKENTVTNDW IPEGEEDDDY LDLEKIFSED DDYIDIVDSL SVSPTDSDVS AGNILQLFHG KSRIQRLNIL NAKFAFNLYR VLKDQVNTFD NIFIAPVGIS TAMGMISLGL KGETHEQVHS ILHFKDFVNA SSKYEITTIH NLFRKLTHRL FRRNFGYTLR SVNDLYIQKQ FPILLDFKTK VREYYFAEAQ IADFSDPAFI SKTNNHIMKL TKGLIKDALE NIDPATQMMI L
靶标信息
The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HC-II; Heparin cofactor 2; Heparin cofactor II; HLS2; leuserpin 2; Protease inhibitor leuserpin-2; serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1; Serpin D1; serpin peptidase inhibitor, clade D (heparin cofactor), member 1
基因别名: AA985900; AI303446; D22S673; HC2; HCF2; HCII; HLS2; LS2; SERPIND1; THPH10
UniProt ID: (Human) P05546, (Mouse) P49182
Entrez Gene ID: (Human) 3053, (Mouse) 15160
