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Invitrogen
Hepatitis B Virus X Monoclonal Antibody (3F6-G10)
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Hepatitis B Virus X Antibody (MA1-81021) in ICC/IF
Cell & bioscience 2022 -
Fig. 3 DNMT1 inhibition attenuated HK-2 cell and human podocyte injury in vitro. A and B The expression of HBx and DNMT1 in HBx-HK-2 cells and HBx-podocytes with or without DNMT1 knockdown was evaluated by western blotting. C and D The localization and expression of HBx and DNMT1 in HBx-HK-2 cells and HBx-podocytes were determined by immunofluorescence. Scale bar: 10 mum. E and F ELISA was conducted to meas... View More
产品信息
MA1-81021
应用
建议稀释比
已发表文章
产品规格
种属反应
Virus
已发表种属
Virus
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
3F6-G10
抗原
HB-Xag-Protein A Fusion protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS with 0.1% BSA
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A suggested positive control for immunohistochemical applications is liver carcinoma/hepatitis B infected liver. This product does not require protein digestion pre-treatment of paraffin embedded sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin embedded sections.
Mouse anti Hepatitis B-X antibody, clone 3F6-G10 recognizes the HB-X antigen of hepatitis virus.
靶标信息
The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. The Hepatitis B X antigen is a 154 amino acid ~17 kDa multifunctional protein involved in the development of liver chirrosis and hepatocellular carcinoma. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
