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Invitrogen
Higenamine Recombinant Mouse Monoclonal Antibody (2B1)
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Higenamine Antibody (MA566464) in SDS-PAGE
SDS-PAGE characterization of Higenamine under reducing conditions. Lane M: Protein marker (kDa); Lane HGN: Purified Higenamine Recombinant Monoclonal (Product # MA566464). Higenamine showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-273.
产品信息
MA566464
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2B1
抗原
Conjugate of HGN hapten and KLH.
偶联物
形式
Liquid
浓度
7.5 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Higenamine is a plant-based alkaloid belonging to the structural class of protoberberines, initially isolated as the active cardiotonic component from Aconitum by Kosuge in 1976. It is a chiral compound with one asymmetric carbon, typically found as a racemic mixture of two enantiomers, (S)-(-)-higenamine and (R)-(+)-higenamine. The empirical formula of higenamine is C16H17NO3, with a molecular weight of 271.272. Higenamine is known for its pharmacological properties, including its role as a beta-adrenergic receptor agonist, which contributes to its cardiotonic effects. It has been studied for its pharmacokinetics and pharmacodynamics in healthy volunteers, highlighting its potential clinical applications in treating cardiovascular diseases. However, further research is needed to optimize its clinical use while ensuring safety and efficacy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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