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Invitrogen
Histone H2B (Biosimilar) Recombinant Human Monoclonal Antibody
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产品信息
MA5-58943
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
形式
Lyophilized
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
25mM histidine, pH 6.2, with 8% sucrose, 0.01% Tween 80
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
产品详细信息
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
This antibody can also be cross referenced by the term Immunomedics patent anti-Histone H2B.
靶标信息
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acetyl-Histone H2; H2B GL105 antibody; H2B histone family member M; H2B histone family member W testis-specific; H2B histone family member W, testis specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B K; H2B type 12; H2B-clustered histone 17; H2B-clustered histone 18; H2B-clustered histone 21; H2B-clustered histone 26; H2B-clustered histone 3; H2B-clustered histone 5; H2B-clustered histone 9; H2B.1 antibody; H2B.E variant histone 1; H2B.M histone; H2B.U histone 1; H2B.W histone 1; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/q; H2B/r; H2B/s; H2BK12ac; H2BK15ac; H2BK5ac; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRA-interacting protein 2; HIST1H2BB antibody; HIST1H3I; HIST2H2BE; histone 1, H2ba; histone 1, H2bb; histone 1, H2bc; histone 1, H2bd; histone 1, H2bg; histone 1, H2bh; histone 1, H2bi; histone 1, H2bj; histone 1, H2bk; histone 1, H2bl; histone 1, H2bm; histone 1, H2bn; histone 1, H2bo; histone 2, H2be; Histone 2B; histone 3, H2bb; histone cluster 1 H2B family member a; histone cluster 1 H2B family member b; histone cluster 1 H2B family member c; histone cluster 1 H2B family member d; histone cluster 1 H2B family member g; histone cluster 1 H2B family member h; histone cluster 1 H2B family member i; histone cluster 1 H2B family member j; histone cluster 1 H2B family member k; histone cluster 1 H2B family member l; histone cluster 1 H2B family member m; histone cluster 1 H2B family member n; histone cluster 1 H2B family member o; histone cluster 1, H2ba; histone cluster 1, H2bb; histone cluster 1, H2bc; histone cluster 1, H2bd; histone cluster 1, H2bg; histone cluster 1, H2bh; histone cluster 1, H2bi; histone cluster 1, H2bj; histone cluster 1, H2bk; histone cluster 1, H2bl; histone cluster 1, H2bm; histone cluster 1, H2bn; histone cluster 1, H2bo; histone cluster 2 H2B family member e; histone cluster 2 H2B family member f; histone cluster 2, H2be; histone cluster 2, H2bf; histone cluster 3 H2B family member b; histone cluster 3, H2bb; histone family member; Histone H2B type 1-A; Histone H2B type 1-B; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-D; Histone H2B type 1-H; Histone H2B type 1-J; Histone H2B type 1-K; Histone H2B type 1-L; Histone H2B type 1-M; Histone H2B type 1-N; Histone H2B type 1-O; Histone H2B type 2-E; Histone H2B type 2-E1; Histone H2B type 2-F; Histone H2B type 2-K1; Histone H2B type 3-B; Histone H2B type F-M; Histone H2B type W-T; Histone H2B, testis; Histone H2B-GL105; Histone H2B.1; Histone H2B.1 A; Histone H2B.1 B; Histone H2B.2; Histone H2B.a; Histone H2B.b; Histone H2B.c; Histone H2B.d; Histone H2B.e; Histone H2B.f; Histone H2B.g; Histone H2B.h; Histone H2B.I; Histone H2B.j; Histone H2B.k; Histone H2B.l; Histone H2B.n; Histone H2B.q; Histone H2B.r; Histone H2B.s; MGC125414; MGC125415; MGC125416; MGC9388; novel histone H2B-like protein; RP1-193B12.10; Testis-specific histone H2B; TSH2B.1; unnamed protein product
基因别名: bA317E16.3; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; GL105; H2B; H2B-GL105; H2B.1; H2B.1A; H2B.1B; H2B.2; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/j; H2B/k; H2B/l; H2B/n; H2B/r; H2B/S; H2Bb; H2BC1; H2BC10; H2BC11; H2BC12; H2BC13; H2BC14; H2BC15; H2BC17; H2BC18; H2BC21; H2BC26; H2BC3; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2BC9; H2BE; H2BE1; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFQ; H2BFR; H2BFT; H2BFU; H2BFWT; H2BGL105; H2BJ; H2BK; H2BK1; H2BM; H2BQ; H2BU1; H2BW1; H2BW2; HIRIP1; HIRIP2; HIST1H2BA; HIST1H2BB; HIST1H2BC; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BH; HIST1H2BI; HIST1H2BJ; HIST1H2BK; HIST1H2BL; HIST1H2BM; HIST1H2BN; HIST1H2BO; HIST2H2BE; HIST2H2BF; HIST3H2BB; hTSH2B; STBP; TH2B; TH2B-175; TSH2B; TSH2B.1
UniProt ID: (Human) Q96A08, (Human) P62807, (Human) P06899, (Human) O60814, (Human) Q99880, (Human) Q99879, (Human) Q99877, (Human) P23527, (Human) Q5QNW6, (Human) Q16778, (Human) Q8N257, (Human) P33778, (Human) Q93079, (Human) A0A2R8Y619, (Human) Q7Z2G1, (Human) P0C1H6
Entrez Gene ID: (Human) 255626, (Human) 8346, (Human) 8970, (Human) 85236, (Human) 8340, (Human) 8342, (Human) 8341, (Human) 8348, (Human) 440689, (Human) 8349, (Human) 128312, (Human) 3018, (Human) 8347, (Human) 3017, (Human) 8339, (Human) 8345, (Human) 114483833, (Human) 158983, (Human) 286436, (Human) 102724334
nucleosome assembly
innate immune response in mucosa
antibacterial humoral response
defense response to bacterium
defense response to Gram-positive bacterium
antimicrobial humoral immune response mediated by antimicrobial peptide
mitotic chromosome condensation
chromatin organization
negative regulation of tumor necrosis factor-mediated signaling pathway
killing of cells of other organism
defense response to Gram-negative bacterium
protein localization to CENP-A containing chromatin
nucleosome disassembly
inflammatory response
plasminogen activation
sperm chromatin condensation
chromosome organization
mononuclear cell migration
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