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Bethyl Laboratories
Human Beta-2 Glycoprotein 1 Polyclonal Antibody
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产品信息
A80-142A
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 6.8 to 7.4
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Goats were immunized with purified human beta-2 glycoprotein 1 of serum or plasma origin. Antiserum was solid phase adsorbed to ensure specificity. The antibody was isolated by affinity chromatography using antigen coupled to agarose beads. Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.
靶标信息
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2GPI; Activated protein C-binding protein; Anticardiolipin cofactor; APC inhibitor; Apo-H; Apolipoprotein H; apolipoprotein H (beta-2-glycoprotein I); B2GPI; beta(2)GPI; Beta-2-glycoprotein 1; Beta-2-glycoprotein I
基因别名: APOH; B2G1; B2GP1; BG
UniProt ID: (Human) P02749
Entrez Gene ID: (Human) 350
negative regulation of endothelial cell proliferation
platelet degranulation
triglyceride metabolic process
aging
blood coagulation, intrinsic pathway
negative regulation of endothelial cell migration
positive regulation of triglyceride catabolic process
negative regulation of angiogenesis
positive regulation of blood coagulation
negative regulation of blood coagulation
organ regeneration
plasminogen activation
negative regulation of myeloid cell apoptotic process
response to triglyceride
triglyceride transport
negative regulation of smooth muscle cell apoptotic process
positive regulation of lipoprotein lipase activity
regulation of fibrinolysis
negative regulation of fibrinolysis
negative regulation of respiratory burst
