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IPO-74 reacts with human leukemia cell line HL-60 and shows a band at MW 127 kDa (reduced) both in immunoprecipitation and Western blotting. In peripheral blood only subsets of B cells, T cells, neutrophilic and eosinophilic granulocytes are positive. All monocytes are positive. Cell lines U937 and K562 are positive, while Daudy, Raji, Jurkat and Molt-4 are negative, as are IL2-dependent T cell lines/clones.
The lymphocytic marker is a gene target that plays a crucial role in the identification and characterization of lymphocytes, a type of white blood cell. Lymphocytes are key components of the immune system and are responsible for defending the body against infections and diseases. The lymphocytic marker gene helps in distinguishing lymphocytes from other cell types and enables researchers to study their function and behavior. By targeting this gene, scientists can gain insights into the immune response, develop diagnostic tools, and design therapeutic strategies for various immune-related disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。