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Invitrogen
Hyoscyamine Recombinant Mouse Monoclonal Antibody (3F12)
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Hyoscyamine Antibody (MA566460) in SDS-PAGE
SDS-PAGE characterization of Hyoscyamine under reducing conditions. Lane M: Protein marker (kDa); Lane HSM: Purified Hyoscyamine Recombinant Monoclonal (Product # MA566460). Hyoscyamine showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-272.
产品信息
MA566460
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3F12
抗原
Conjugate of HSM hapten and KLH.
偶联物
形式
Liquid
浓度
3.6 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Hyoscyamine is a tropane alkaloid extracted from the leaves of Hyoscyamus niger and other plants like Scopolia lurida, known for its diverse pharmacological properties including analgesic, anti-inflammatory, anti-convulsive, hypotensive, and anticholinergic effects. The gene encoding hyoscyamine 6-beta-hydroxylase (H6H), an enzyme crucial in the biosynthesis of tropane alkaloids, has been cloned from Hyoscyamus niger and Scopolia lurida, and overexpressed in hairy root cultures to enhance production. Structurally, hyoscyamine is characterized by its ability to decrease gastrointestinal tract motion and secretion, making it effective in treating various disorders such as bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Furthermore, hyoscyamine is utilized as an anticholinergic agent in managing Parkinson's disease and genitourinary symptoms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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