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Invitrogen
ICAM-2 Recombinant Mouse Monoclonal Antibody (K56046_6H3)
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ICAM-2 Antibody (MA564472) in WB
Western blot analysis of ICAM-2 in Jurkat lysate (15 µg). Samples were incubated with ICAM-2 recombinant monoclonal (Product # MA564472) using a dilution of 1 µg/mL followed by peroxidase conjugated goat anti-mouse IgG. Sample was run on 6-18% SDS-PAGE under reducing conditions and blotted onto nitrocellulose membrane. ICAM2 band was visualized using ECL Western Blotting Substrate.
产品信息
MA564472
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K56046_6H3
抗原
Recombinant human ICAM2 (aa 31-220).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.09% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VRPKKLAVEP KGSLEVNCST TCNQPEVGGL ETSLDKILLD EQAQWKHYLV SNISHDTVLQ CHFTCSGKQE SMNSNVSVYQ PPRQVILTLQ PTLVAVGKSF TIECRVPTVE PLDSLTLFLF RGNETLHYET FGKAAPAPQE ATATFNSTAD REDGHRNFSC LAVLDLMSRG GNIFHKHSAP KMLEIYEPVS
Highest antigen sequence identity to the following orthologs: Mouse - 57%, Rat - 33%, Pig - 55%, Cynomolgus monkey - 83%.
靶标信息
ICAM-2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. ICAM-2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. Diseases associated with ICAM2 include Colon Carcinoma In Situ.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD102; ICAM-2; Intercellular adhesion molecule 2; RP23-418O11.10-001
基因别名: CD102; ICAM2
UniProt ID: (Human) P13598
Entrez Gene ID: (Human) 3384
