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Invitrogen
IFT172 Polyclonal Antibody
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产品信息
PA5-25305
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human IFT172
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with rat based on sequence homology.
靶标信息
IFT172 is required for the maintenance and formation of cilia. IT plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: intraflagellar transport 172 homolog; intraflagellar transport 172 protein; Intraflagellar transport protein 172 homolog; Protein wimple; selective LIM binding factor homolog; selective LIM-binding factor Wimple; wimple homolog
基因别名: 4930553F24Rik; avc1; BBS20; IFT172; KIAA1179; NPHP17; osm-1; RP71; SLB; SRTD10; Wim
UniProt ID: (Human) Q9UG01, (Mouse) Q6VH22
Entrez Gene ID: (Human) 26160, (Mouse) 67661
neural tube closure
heart looping
Notch signaling pathway
smoothened signaling pathway
brain development
epidermis development
dorsal/ventral pattern formation
protein processing
spinal cord motor neuron differentiation
cytoplasmic microtubule organization
cilium assembly
positive regulation of smoothened signaling pathway
negative regulation of epithelial cell proliferation
palate development
limb development
bone development
hindgut development
left/right axis specification
negative regulation of transcription from RNA polymerase II promoter
neural tube formation
multicellular organism development
determination of left/right symmetry
heart development
regulation of smoothened signaling pathway
neural tube development
cilium morphogenesis
