IGF1 Recombinant Rabbit Monoclonal Antibody (8W6E4)

insulin receptor binding insulin-like growth factor receptor binding integrin binding hormone activity protein binding growth factor activity protein kinase activator activity transmembrane receptor protein tyrosine kinase activator activity receptor agonist activity steroid binding protein serine/threonine kinase activator activity growth factor

skeletal system development osteoblast differentiation cell activation epithelial to mesenchymal transition blood vessel remodeling signal transduction Ras protein signal transduction nervous system development muscle organ development circadian rhythm cell proliferation positive regulation of cell proliferation negative regulation of cell proliferation insulin receptor signaling pathway response to heat glycolate metabolic process glial cell differentiation regulation of gene expression positive regulation of glycoprotein biosynthetic process positive regulation of cardiac muscle hypertrophy positive regulation of gene expression negative regulation of gene expression skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration muscle hypertrophy myotube differentiation myotube cell development positive regulation of smooth muscle cell migration cerebellar granule cell precursor proliferation positive regulation of cerebellar granule cell precursor proliferation proteoglycan biosynthetic process lung development positive regulation of cell migration androgen receptor signaling pathway mammary gland development exocrine pancreas development positive regulation of myelination activation of protein kinase B activity negative regulation of interleukin-1 beta production negative regulation of tumor necrosis factor production regulation of establishment or maintenance of cell polarity negative regulation of smooth muscle cell apoptotic process multicellular organism growth bone mineralization involved in bone maturation wound healing positive regulation of activated T cell proliferation negative regulation of apoptotic process positive regulation of DNA binding positive regulation of MAPK cascade protein kinase B signaling positive regulation of insulin-like growth factor receptor signaling pathway type B pancreatic cell proliferation regulation of nitric oxide biosynthetic process myoblast differentiation positive regulation of osteoblast differentiation positive regulation of glycogen biosynthetic process positive regulation of glycolytic process positive regulation of mitotic nuclear division positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of glucose import positive regulation of Ras protein signal transduction insulin-like growth factor receptor signaling pathway positive regulation of fibroblast proliferation lung alveolus development cell development positive regulation of smooth muscle cell proliferation branching morphogenesis of an epithelial tube inner ear development chondroitin sulfate proteoglycan biosynthetic process positive regulation of epithelial cell proliferation positive regulation of protein secretion protein stabilization regulation of protein metabolic process myoblast proliferation positive regulation of protein kinase B signaling negative regulation of oocyte development growth hormone receptor signaling pathway lung vasculature development lung lobe morphogenesis Type I pneumocyte differentiation Type II pneumocyte differentiation prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis prostate gland growth prostate gland epithelium morphogenesis prostate gland stromal morphogenesis negative regulation of androgen receptor signaling pathway positive regulation of cell growth involved in cardiac muscle cell development negative regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade positive regulation of calcineurin-NFAT signaling cascade cellular response to glucose stimulus negative regulation of release of cytochrome c from mitochondria extrinsic apoptotic signaling pathway in absence of ligand receptor signaling pathway via STAT postsynaptic modulation of chemical synaptic transmission negative regulation of neuroinflammatory response negative regulation of beta-amyloid formation positive regulation of trophectodermal cell proliferation cellular response to beta-amyloid positive regulation of type B pancreatic cell proliferation positive regulation of vascular smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell apoptotic process cellular response to insulin-like growth factor stimulus positive regulation of myoblast proliferation positive regulation of transcription regulatory region DNA binding negative regulation of apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway regulation of protein phosphorylation regulation of translation memory phosphatidylinositol 3-kinase signaling positive regulation of phosphatidylinositol 3-kinase signaling water homeostasis positive regulation of cell growth regulation of intracellular steroid hormone receptor signaling pathway positive regulation of protein import into nucleus, translocation regulation of cell proliferation positive regulation of tyrosine phosphorylation of Stat5 protein negative regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of fat cell differentiation positive regulation of DNA replication phosphatidylinositol-mediated signaling positive regulation of peptidyl-tyrosine phosphorylation detection of mechanical stimulus involved in sensory perception regulation of calcium ion transport ERK1 and ERK2 cascade positive regulation of protein serine/threonine kinase activity positive regulation of steroid hormone biosynthetic process negative regulation of neuron death