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Abnova
IGF2BP2 Monoclonal Antibody (4C6)
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产品信息
H00010644-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
4C6
抗原
IGF2BP2 (AAH21290, 1 a.a. approximately 598 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MNKLYIGNLS PAVTADDLRQ LFGDRKLPLA GQVLLKSGYA FVDYPDQNWA IRAIETLSGK VELHGKIMEV DYSVSKKLRS RKIQIRNIPP HLQWEVLDGL LAQYGTVENV EQVNTDTETA VVNVTYATRE EAKIAMEKLS GHQFENYSFK ISYIPDEEVS SPSPPQRAQR GDHSSREQGH APGGTSQARQ IDFPLRILVP TQFVGAIIGK EGLTIKNITK QTQSRVDIHR KENSGAAEKP VTIHATPEGT SEACRMILEI MQKEADETKL AEEIPLKILA HNGLVGRLIG KEGRNLKKIE HETGTKITIS SLQDLSIYNP ERTITVKGTV EACASAEIEI MKKLREAFEN DMLAVNQQAN LIPGLNLSAL GIFSTGLSVL SPPAGPRGAP PAAPYHPFTT HSGYFSSLYP HHQFGPFPHH HSYPEQEIVN LFIPTQAVGA IIGKKGAHIK QLARFAGASI KIAPAEGPDV SERMVIITGP PEAQFKAQGR IFGKLKEENF FNPKEEVKLE AHIRVPSSTA GRVIGKGGKT VNELQNLTSA EVIVPRDQTP DENEEVIVRI IGHFFASQTA QRKIREIVQQ VKQQEQKYPQ GVASQRSK
靶标信息
IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; IGF2 mRNA-binding protein 2; insulin-like growth factor 2 mRNA binding protein 2; Insulin-like growth factor 2 mRNA-binding protein 2; p62; VICKZ family member 2
基因别名: IGF2BP2; IMP-2; IMP2; VICKZ2
UniProt ID: (Human) Q9Y6M1
Entrez Gene ID: (Human) 10644
