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Invitrogen
IGFBP2 Polyclonal Antibody
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FIGURE: 1 / 3
IGFBP2 Antibody (PA5-85534) in ICC/IF
IGFBP2 Polyclonal Antibody detects IGFBP2 protein at cytoplasm by immunofluorescent analysis. Sample: Huh-7 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: IGFBP2 protein stained by IGFBP2 Polyclonal Antibody (Product # PA5-85534) diluted at 1:500. Blue: Hoechst 33342 staining.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-85534
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human IGFBP2. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (83%), Rat (82%), Pig (91%), Sheep (84%), Bovine (87%).
Positive Control: SK-N-SH.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IBP-2; IGF binding protein 2; IGFBP; Insulin like growth factor binding protein; Insulin-like growth factor-binding protein 2; OTTHUMP00000207753
Gene Aliases: BP2; IBP2; IGFBP2
Entrez Gene ID: (Human) 3485
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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