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Invitrogen
IGHMBP2 Polyclonal Antibody
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产品信息
PA5-68168
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from human IGHMBP2.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Predicted to react with Mouse and Rat samples.
靶标信息
5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation. DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AEP; antifreeze enhancer-binding protein; Antifreeze enhancer-binding protein ortholog; ATP-dependent helicase IGHMBP2; cardiac transcription factor 1; DNA-binding protein SMUBP-2; GF-1; Glial factor 1; Immunoglobulin mu-binding protein 2; immunoglobulin S mu binding protein 2; neuromuscular degeneration; p110 subunit
基因别名: AEP; Catf1; IGHMBP2; nmd; RIPE3b1; sma; Smbp-2; SMBP2; SMUBP2
UniProt ID: (Rat) Q9EQN5
Entrez Gene ID: (Mouse) 20589, (Rat) 29532
tRNA binding
nucleotide binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
nucleic acid binding
DNA binding
RNA binding
helicase activity
ATP binding
DNA-dependent ATPase activity
transcription factor binding
RNA-dependent ATPase activity
zinc ion binding
hydrolase activity
ATP-dependent 5'-3' RNA helicase activity
ribosome binding
ATP-dependent 5'-3' DNA helicase activity
metal ion binding
protein self-association
DNA metabolism protein
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
translation
spinal cord motor neuron differentiation
DNA duplex unwinding
protein homooligomerization
metabolic process
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