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Invitrogen
IGSF11 Monoclonal Antibody (OTI1B9)
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IGSF11 Antibody (MA5-26621) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human ovary tissue. To expose target proteins, 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a IGSF11 monoclonal antibody (Product # MA5-26621).
产品信息
MA5-26621
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI1B9
抗原
Human recombinant protein fragment corresponding to amino acids 23-241 of IGSF11 produced in E.coli
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Immunoglobulin superfamily member 11 (IGSF11) is a gene located on chromosome 3q13.3, encoding a transmembrane protein that belongs to the immunoglobulin superfamily. IGSF11 is known for its expression in the brain, where it plays a role in neuron-to-neuron adhesion and synaptic organization. The protein is involved in processes such as synapse formation and stabilization, impacting neural connectivity and signaling pathways. IGSF11 is also expressed in other tissues, including the gastrointestinal tract, where it can contribute to cell adhesion functions. Research has linked IGSF11 to cancer biology, as its expression is altered in various cancers, potentially influencing tumor cell adhesion and metastasis. Its role in modulating cell signaling pathways makes it an interesting target for therapeutic interventions in both neurological disorders and cancer. Current studies are focusing on its functional implications in synaptic plasticity and tumor progression, providing valuable insights into IGSF11's diverse biological roles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: brain and testis-specific immunoglobin superfamily protein; Brain and testis-specific immunoglobulin superfamily protein; Bt-IGSF; cancer/testis antigen 119; CXADR like 1; IgSF11; Immunoglobulin superfamily member 11; immunoglobulin superfamily, member 11; V-set and immunoglobulin domain containing 3; V-set and immunoglobulin domain-containing protein 3
基因别名: BT-IgSF; BTIGSF; CT119; CXADRL1; IGSF11; Igsf13; VSIG3
UniProt ID: (Human) Q5DX21
Entrez Gene ID: (Human) 152404
