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Invitrogen
IGSF3 Polyclonal Antibody
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IGSF3 Antibody (PA5-120162) in WB
Western blot analysis of IGSF3 in extracts of various cell lines. Samples were incubated with IGSF3 Polyclonal antibody (Product # PA5-120162) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-120162
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 350-562 of human IGSF3 (NP_001007238.1).
偶联物
形式
Liquid
浓度
1.17 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: 293T, MCF7. The target is usually found in the following locations: Membrane, Single-pass type I membrane protein.
Immunogen sequence: KVAKESDSVF VLKIYHLRQE DSGKYNCRVT EREKTVTGEF IDKESKRPKN IPIIVLPLKS SISVEVASNA SVILEGEDLR FSCSVRTAGR PQGRFSVIWQ LVDRQNRRSN IMWLDRDGTV QPGSSYWERS SFGGVQMEQV QPNSFSLGIF NSRKEDEGQY ECHVTEWVRA VDGEWQIVGE RRASTPISIT ALEMGFAVTA ISRTPGVTYS DSF
靶标信息
IGSF3 (immunoglobulin superfamily, member 3), also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EWI-3; Glu-Trp-Ile EWI motif-containing protein 3; IgSF3; immunoglobin superfamily, member 3; Immunoglobulin superfamily member 3; RP4-781D12.1
基因别名: EWI-3; EWI3; IGSF3; KIAA0466; LCDD; V8
UniProt ID: (Human) O75054
Entrez Gene ID: (Human) 3321
