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Invitrogen
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Antibody tested in Indirect ELISA
IGSF3 (immunoglobulin superfamily, member 3), also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EWI-3; Glu-Trp-Ile EWI motif-containing protein 3; IgSF3; immunoglobin superfamily, member 3; Immunoglobulin superfamily member 3; RP4-781D12.1
基因别名: EWI-3; EWI3; IGSF3; KIAA0466; LCDD; V8
UniProt ID: (Human) O75054
Entrez Gene ID: (Human) 3321