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AA Sequence of recombinant protein: MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL.
Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IL-11. Anti-Human IL-11 specific antibody was purified by affinity chromatography employing an immobilized Human IL-11 matrix.
Sandwich ELISA: To detect Human IL-11 by sandwich ELISA (using 100 µL/well) a concentration of 0.5-2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human IL-11 (500-P01BT) as a detection antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Human IL-11.
Western Blot: To detect Human IL-11 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. When used in conjunction with compatible secondary reagents the detection limit for Recombinant Human IL-11 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Adipogenesis inhibitory factor; AGIF; il 11; IL-11; IL-11ra; IL10RA; IL11 inhibitor; ILN; Interleukin; Interleukin-11; Interleukin11; MGC2146; oprelvekin
基因别名: AGIF; IL-11; IL11
UniProt ID: (Human) P20809
Entrez Gene ID: (Human) 3589
分子生物学功能: interleukin superfamily