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Invitrogen
IL-11 Recombinant Rabbit Monoclonal Antibody (R4P1-C12)
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IL-11 Antibody (760001R) in Flow
Flow cytometry analysis of IL-11 Recombinant Rabbit Monoclonal Antibody (R4P1-C12) (Product # 760001R) was performed using HT-1080 and T-47D cells. Cells were stained with 1 µg of IL-11 Recombinant Rabbit Monoclonal Antibody (R4P1-C12) (Product # 760001R) followed by Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor™ Plus 647 (Product # A32733, 1:1,000). IL-11 higher expression was observed in HT-1080 (pink histogram) in comparison to T-47D (blue histogram). Viable cells were used for analysis, as determined ... View More
产品信息
760001R
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
R4P1-C12
抗原
Protein corresponding to human IL-11 [aa22-aa199]
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
Recombinant Rabbit monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency.
It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
靶标信息
Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adipogenesis inhibitory factor; AGIF; il 11; IL-11; IL-11ra; IL10RA; IL11 inhibitor; ILN; Interleukin; Interleukin-11; Interleukin11; MGC2146; oprelvekin
基因别名: AGIF; IL-11; IL11
UniProt ID: (Human) P20809
Entrez Gene ID: (Human) 3589
cell-cell signaling
positive regulation of cell proliferation
B cell differentiation
megakaryocyte differentiation
positive regulation of peptidyl-serine phosphorylation
positive regulation of MAPK cascade
fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of hormone secretion
positive regulation of peptidyl-tyrosine phosphorylation
regulation of complement-dependent cytotoxicity
negative regulation of endothelial cell apoptotic process
