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Invitrogen
IL-12 p70 Monoclonal Antibody (C11.5)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
AHC9122
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human,
Non-human primate
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
C11.5
抗原
Recombinant human IL-12, p40 expressed in CHO cells.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
500 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.2
内含物
no preservative
保存条件
-80°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody recognizes the p40 subunit and the p70 heterodimer of human IL-12, and can be used as a capture antibody in ELISA assays. It does not effectively neutralize IL-12.
AHC9122 is >98% pure by SDS-PAGE. Further dilutions should be made in medium or buffered solution with carrier protein, such as PBS with 0.1-1.0% BSA. The addition of a preservative is also recommended for long term storage. For maximal stability, apportion into working aliquots and store at -70°C, avoiding repeated freeze-thaw cycles.
靶标信息
IL-12 p70, also known as interleukin-12, is a cytokine that plays a critical role in the immune system's response to infections and cancer. It is produced by immune cells, including dendritic cells, macrophages, and B cells, in response to certain pathogens and tumor cells. IL-12 p70 stimulates the production of interferon-gamma and other cytokines, which promote the activation and proliferation of T cells and natural killer cells. IL-12 p70 has been studied as a potential therapeutic target for various diseases and conditions, including infectious diseases, autoimmune disorders, and cancer. It has been shown to enhance immune responses against certain infections and tumors, and to modulate inflammatory responses in autoimmune diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 20C2; CLMF p35; CLMF p40; Cytotoxic lymphocyte maturation factor 35 kDa subunit; Cytotoxic lymphocyte maturation factor 40 kDa subunit; il 12; IL 12p70; IL-12 p75; IL-12 subunit p35; IL-12 subunit p40; IL-12A; IL-12B; IL12A/B; IL12AB; ILN; Interleukin; Interleukin-12 p70; Interleukin-12 subunit alpha; Interleukin-12 subunit beta; MGC151228; MGC151232; NK cell stimulatory factor chain 1; NK cell stimulatory factor chain 2; NKSF1; NKSF2
基因别名: IL12A; IL12B; NKSF1; NKSF2
Entrez Gene ID: (Human) 3592, (Human) 3593
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
