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IL-7 Polyclonal Antibody, Biotin
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产品信息
209-406-B94
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL-7 protein.
偶联物
形式
Lyophilized
浓度
1 mg/mL
规格
100 µg
纯化类型
Ion-exchange chromatography
保存液
0.02M potassium phosphate, pH 7.2, with 10mg/mL BSA, 0.15M NaCl
内含物
0.01% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human IL-7 in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
靶标信息
Interleukin 7 (IL-7) is a hematopoietic cytokine that is constitutively produced by stromal cells from the bone marrow and thymus. IL-7 signals through the IL-7R to promote the differentiation of hematopoietic stem cells to lymphoid precursor cells, which give rise to T cells, B cells, and natural killer cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD127; CD127 antigen; CDw127; cytokine; H-IL-7; IL-7; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL7R; IL-7 receptor alpha chain; ILN; Interleukin; interleukin 7 precursor; interleukin 7 receptor alpha chain; Interleukin-7; interleukin-7 receptor precursor; Interleukin-7 receptor subunit alpha; Interleukin7; M-IL-7; soluble interleukin-7 receptor; unnamed protein product
基因别名: CD127; CDW127; IL-7; IL-7R-alpha; IL-7Ralpha; IL7; IL7R; IL7RA; IL7Ralpha; ILRA; IMD104; IMD130; lnc-IL7R; sIL-7R
UniProt ID: (Human) P13232, (Human) P16871
Entrez Gene ID: (Human) 3574, (Human) 3575
positive regulation of cytokine-mediated signaling pathway
T cell lineage commitment
immune response
humoral immune response
cell-cell signaling
positive regulation of cell proliferation
organ morphogenesis
regulation of gene expression
positive regulation of gene expression
cytokine-mediated signaling pathway
cellular homeostasis
positive regulation of B cell proliferation
positive regulation of chemokine production
organ growth
interleukin-7-mediated signaling pathway
B cell proliferation
negative regulation of apoptotic process
bone resorption
positive regulation of B cell differentiation
positive regulation of T cell differentiation
positive regulation of organ growth
homeostasis of number of cells within a tissue
extrinsic apoptotic signaling pathway
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
regulation of DNA recombination
cell morphogenesis
B cell homeostasis
T cell mediated cytotoxicity
negative regulation of T cell mediated cytotoxicity
signal transduction
cell surface receptor signaling pathway
regulation of cell size
gene expression
hemopoiesis
T cell differentiation
T cell differentiation in thymus
positive regulation of T cell differentiation in thymus
T cell homeostasis
positive regulation of JAK-STAT cascade
lymph node development
defense response to Gram-positive bacterium
negative regulation of T cell apoptotic process
positive regulation of STAT cascade
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