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Invitrogen
IL36B Polyclonal Antibody
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IL36B Antibody (PA5-81415) in IHC (P)
Immunohistochemical staining of mouse IL36B in mouse intestine with IL36B Polyclonal Antibody (Product # PA5-81415, 1:1,000, formalin-fixed paraffin embedded sections). Left panel: tissue incubated with primary antibody; Right panel: tissue incubated with mixture of primary antibody and antigen (recombinant protein).
产品信息
PA5-81415
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
已发表种属
C. elegans
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Mouse IL-36B/IL-1F8 protein (Met1-Lys183)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Mouse IL-36B/IL-1F8.
靶标信息
IL-36B is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. IL-36B is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP. Like the related proteins IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown. The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: IL-1F8; Interleukin; Interleukin-1 family member 8; Interleukin-36 beta
基因别名: 2310043N20Rik; Fil1e; Il1f8; Il36b
UniProt ID: (Mouse) Q9D6Z6
Entrez Gene ID: (Mouse) 69677
