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Invitrogen
INCA1 Polyclonal Antibody
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产品信息
PA5-60689
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KKRRPCLEGM QQQGLGGVPA RVRAVTYHLE DLRRRQSIIN ELKKAQWGSS GAASEPVVLG EEGCGFPSTN EYPD
Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 68%.
靶标信息
Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor (PubMed:21540187). Inhibits cell growth and cell proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Inhibitor of CDK interacting with cyclin A1; Protein INCA1
基因别名: HSD45; INCA1
UniProt ID: (Human) Q0VD86
Entrez Gene ID: (Human) 388324
