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Abnova
INS Monoclonal Antibody (7C8)
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产品信息
H00003630-M02
产品规格
宿主/亚型
Mouse
/ IgG3, kappa
分类
Monoclonal
类型
Antibody
克隆号
7C8
抗原
KLH-conjugated human Proinsulin peptide (NP_000198, 48 a.a. approximately 62 a.a)
偶联物
形式
Liquid
浓度
See Label
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: CFFYTPKTRR EAEDLQ
靶标信息
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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