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Invitrogen
INSRR Polyclonal Antibody
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产品信息
PA5-76119
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein of human INSRR.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
INSRR, insulin receptor-related receptor, is a member of the insulin receptor (IR) family. INSRR does not bind insulin-like molecules, but is similar to INSR in tyrosine kinase activity. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Insulin receptor-related protein; insulin receptor-related receptor; IR-related receptor; IRR
基因别名: INSRR; IRR; Sirr
UniProt ID: (Human) P14616, (Mouse) Q9WTL4, (Rat) Q64716
Entrez Gene ID: (Human) 3645, (Mouse) 23920, (Rat) 60663
transmembrane receptor protein tyrosine kinase activity
ATP binding
phosphatidylinositol 3-kinase binding
insulin receptor substrate binding
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
transmembrane signal receptor
