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Rockland
IPO-38 Monoclonal Antibody (IPO-38)
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IPO-38 Antibody (200-301-278) in IHC (P)
Immunohistochemistry of Mouse anti-IPO-38 antibody. Tissue: human skin. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: anti-IPO 38 antibody at 10 µg/mL for 1 h at RT. Secondary antibody: Peroxidase mouse secondary antibody at 1:10,000 for 45 min at RT. Staining: IPO-38 as precipitated red signal with hematoxylin purple nuclear counterstain.
产品信息
200-301-278
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgM, kappa
分类
Monoclonal
类型
Antibody
克隆号
IPO-38
抗原
A BALB/c mouse was immunized with spleen cells of a human patient with hairy cell leukemia.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.02M potassium phosphate, pH 7.2, with 0.5M NaCl
内含物
0.01% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Reacts with a 14 -16 kDa protein as demonstrated by western blot analysis on the Raji cell line. This antigen was detected after 12h of PHA-induced activation in the early G1 phase but absent in non-stimulated lymphocytes. Cross reactivity is likely to occur with mouse and rat. Reactivity with other sources has not been determined.
靶标信息
IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin's disease and non-Hodgkin's lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 can be a useful marker of cell proliferation during monitoring of tumor progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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