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Invitrogen
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IQCG is a protein coding gene. Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp434B227; Dynein regulatory complex protein 9; dynein regulatory complex subunit 9; IQ domain-containing protein G
基因别名: 2400003L07Rik; CFAP122; DRC9; esgd12d; G1-374-12; IQCG; repro1; stubby12d
UniProt ID: (Human) Q9H095, (Mouse) Q80W32
Entrez Gene ID: (Human) 84223, (Mouse) 69707