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Abnova
IQWD1 Polyclonal Antibody, MaxPab™
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产品信息
H00055827-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IQWD1 (AAH25262.1, 1 a.a. approximately 513 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLSRWFEEAS EVAQSNRGRG RSRPRGGTSQ SDISTLPTVP SSPDLEVSET AMEVDTPAEQ FLQPSTSSTM SAQAHSTSSP TESPHSTPLL SSPDSEQRQS VEASGHHTHH QSDNNNEKLS PKPGTGEPVL SLHYSTEGTT TSTIKLNFTD EWSSIASSSR GIGSHCKSEG QEESFVPQSS VQPPEGDSET KAPEESSEDA TKYQEGVSAE NPVENHINIT QSDKFTAKPL DSNSGERNDL NLDRSCGVPE ESASSEKAKE PETSDQTSTE SATNENNTNP EPQFQTEATG PSAHEETSTR DSALQDTDDS DDDPVLIPGA RYRAGPGDRR SAVARIQEFF RRRKERKEME ELDTLNIRRP LVKMVYKGHR NSRTMIKEAN FWGANFVMSG SDCGHIFIWD RHTAEHLMLL EADNHVVNCL QPHPFDPILA SSGIDYDIKI WSPLEESRIF NRKLADEVIT RNELMLEETR NTITVPASFM LRMLASLNHI RADRLEGDRS EGSGQENENE DEE
靶标信息
NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Androgen receptor complex-associated protein; ARCAP; DDB1- and CUL4-associated factor 6; IQ motif and WD repeat-containing protein 1; IQ motif and WD repeats 1; NRIP; Nuclear receptor interaction protein
基因别名: 1200006M05Rik; ARCAP; DCAF6; IQWD1; MSTP055; NRIP; PC326
UniProt ID: (Human) Q58WW2
Entrez Gene ID: (Human) 55827
