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Invitrogen
IRAK-M Polyclonal Antibody
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图: 1 / 5
IRAK-M Antibody (PA5-17473) in ICC/IF
Immunofluorescence analysis of Interleukin-1 receptor-associated kinase 3 was performed using 70% confluent log phase THP-1 and THP-1 differentiated with PMA (200 nM for 6 hours). The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with IRAK-M Polyclonal Antibody (Product # PA5-17473) at 1:100 dilution in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Donkey anti-Rabbit ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-17473
产品规格
种属反应
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues near the carboxy-terminus of human IRAK-M
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
29 µg/mL
规格
2.9 µg
纯化类型
Protein A
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
It is not recommended to aliquot this antibody.
靶标信息
IRAK3 serine/threonine kinase or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which are essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ13601; IL-1 receptor-associated kinase M; Inactive IL-1 receptor-associated kinase 3; Interleukin-1 receptor-associated kinase 3; IRAK-3; IRAK-M
基因别名: IRAK3
Entrez Gene ID: (Human) 11213
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
