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Positive test controls include: HeLa. The target is usually found in the following locations: Nucleus.
Immunogen sequence: PHWRKRNIEG KQYLSNMGTR GSYLLPGMAS FVTSNKPDLQ VTIKEESNPV PYNSSWPPFQ DLPLSSSMTP ASSSSRPDRE TRASVIKKTS DITQARVKSC
IRF2 belongs to the interferon regulatory factor family. IRF2 regulates the transcription regulation important to cell proliferation as well as immune responses by binding to the upstream regulatory region of type I IFN and IFNinducible MHC class I genes (the interferon consensus sequence (ICS)) and repression of those genes. However, IRF2 also functions as a transcriptional activator of histone H4 by interactions with NF-kappa B.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp686F0244; Interferon regulatory factor 2; IRF-2; OTTHUMP00000218576; OTTHUMP00000218580
基因别名: IRF-2; IRF2
UniProt ID: (Human) P14316
Entrez Gene ID: (Human) 3660