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This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Interferon regulatory factor 6; IRF-6
基因别名: AI876454; E230028I05Rik; IRF6; LPS; mirf6; OFC6; PIT; PPS; PPS1; VWS; VWS1
UniProt ID: (Human) G0ZTL0, (Mouse) P97431
Entrez Gene ID: (Human) 3664, (Rat) 364081, (Mouse) 54139