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Abnova
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Sequence of this protein is as follows: MGDPPKKKRL ISLCVGCGNQ IHDQYILRVS PDLEWHAACL KCAECNQYLD ESCTCFVRDG KTYCKRDYIR LYGIKCAKCS IGFSKNDFVM RARSKVYHIE CFRCVACSRQ LIPGDEFALR EDGLFCRADH DVVERASLGA GDPLSPLHPA RPLQMAAEPI SARQPALRPH VHKQPEKTTR VRTVLNEKQL HTLRTCYAAN PRPDALMKEQ LVEMTGLSPR VIRVWFQNKR CKDKKRSIMM KQLQQQQPND KTNIQGMTGT PMVAASPERH DGGLQANPVE VQSYQPPWKV LSDFALQSDI DQPAFQQLVN FSEGGPGSNS TGSEVASMSS QLPDTPNSMV ASPIEA
This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
仅用于科研。不用于诊断过程。未经明确授权不得转售。