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Invitrogen
ITGA3 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1303)
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产品信息
MA5-54502
产品规格
种属反应
Human
宿主/亚型
Alpaca
/ VHH
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
SAA1303
抗原
Recombinant Human CD49c/ITGA3.
偶联物
形式
Liquid
浓度
1.09 mg/mL
纯化类型
Metal-chelate chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Compatible with Direct ELISA
靶标信息
ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha 3 subunit of VLA-3 receptor; Alpha3 integrin; antigen CD49C; antigen identified by monoclonal antibody J143; CD49 antigen-like family member C; CD49c; CD49c antigen; FLJ34631; FLJ34704; FRP-2; Galactoprotein B3; GAPB3; integrin alpha 3; Integrin alpha-3; Integrin alpha3; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); testicular tissue protein Li 96; testicular tissue protein Li 98; very late activation protein 3 receptor, alpha-3 subunit; VLA-3 subunit alpha
基因别名: CD49C; FRP-2; GAP-B3; GAPB3; ILNEB; ITGA3; MSK18; VCA-2; VL3A; VLA3a
UniProt ID: (Human) P26006
Entrez Gene ID: (Human) 3675
neuron migration
cell-matrix adhesion
integrin-mediated signaling pathway
heart development
memory
positive regulation of gene expression
positive regulation of epithelial cell migration
positive regulation of cell-substrate adhesion
positive regulation of neuron projection development
regulation of transforming growth factor beta receptor signaling pathway
regulation of Wnt signaling pathway
extracellular matrix organization
lung development
regulation of BMP signaling pathway
negative regulation of cell projection organization
response to gonadotropin
negative regulation of Rho protein signal transduction
exploration behavior
response to drug
skin development
mesodermal cell differentiation
leukocyte migration
maternal process involved in female pregnancy
nephron development
positive regulation of establishment of protein localization to plasma membrane
dendritic spine maintenance
renal filtration
