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Invitrogen
ITGA5 Polyclonal Antibody
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ITGA5 Antibody (PA5-78027) in WB
Western Blot using ITGA5 Polyclonal Antibody (Product # PA5-78027). Mouse tissue extract (50 µg) was separated by 5% SDS-PAGE, and the membrane was blotted with ITGA5 Polyclonal Antibody (Product # PA5-78027) diluted at 1:5,000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
产品信息
PA5-78027
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the Extracellular domain of human Integrin alpha 5. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1.45 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: MDA-MB-231, MDA-MB-231 membrane fraction extract, mouse liver, rat liver
Predicted Reactivity: Bovine (85%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD49 antigen-like family member E; CD49e; fibronectin receptor alpha polypeptide; Fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; integrin alpha 5; integrin alpha 5 (fibronectin receptor alpha); Integrin alpha-5; Integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); very late activation protein 5, alpha subunit; VLA-5
基因别名: CD49e; FNRA; ITGA5; Itga5_retired; VLA-5; VLA5; VLA5A
UniProt ID: (Human) P08648, (Mouse) P11688
Entrez Gene ID: (Human) 3678, (Mouse) 16402, (Rat) 315346
angiogenesis
cell-substrate junction assembly
cell adhesion
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
leukocyte cell-cell adhesion
integrin-mediated signaling pathway
memory
positive regulation of cell-substrate adhesion
extracellular matrix organization
positive regulation of cell migration
positive regulation of vascular endothelial growth factor receptor signaling pathway
cell-substrate adhesion
cell-cell adhesion mediated by integrin
heterotypic cell-cell adhesion
wound healing, spreading of epidermal cells
endodermal cell differentiation
viral entry into host cell
positive regulation of peptidyl-tyrosine phosphorylation
leukocyte migration
positive regulation of sprouting angiogenesis
negative regulation of anoikis
