Invitrogen

ITGA5 Polyclonal Antibody

Name: ITGA5 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-82027

高级验证

4 篇参考文献

查看其他32个CD49e (Integrin alpha 5)抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (5)
高级验证 (2)

ITGA5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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ITGA5 Antibody (PA5-82027) in IHC (P)

Immunohistochemical analysis of ITGA5 in human endometrium using ITGA5 Polyclonal Antibody (Product # PA5-82027) shows weak to moderate membranous positivity in smooth muscle cells.

Product Image Gallery

ITGA5 Antibody — Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of ITGA5 was observed specifically in U2OS cells and in SK-MEL-30 cells using anti-ITGA5 Polyclonal Antibody (Product #PA5-82027) in western blot. The relative expression levels of ITGA5 within each cell line is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image ITGA5 Polyclonal Antibody

产品信息

PA5-82027

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

查看2篇已发表文章 2篇已发表文章

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:500-1:1,000

亲和纯化 (AP)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse

已发表种属

C. elegans, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human ITGA5. Recombinant protein control fragment (Product #RP-102172).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2789188

产品详细信息

Immunogen sequence: DQPQKEEDLG PAVHHVYELI NQGPSSISQG VLELSCPQAL EGQQLLYVTR VTGLNCTTNH PINPKGLELD PEGSLHHQQK REAPSRSSAS SGPQILKCPE AECFRLRCEL GPLHQQESQS LQLHFRVWA

Highest antigen sequence indentity to the following orthologs: Mouse - 85%, Rat - 82%.

靶标信息

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: CD49 antigen-like family member E; CD49e; fibronectin receptor alpha polypeptide; Fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; integrin alpha 5; Integrin alpha-5; Integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); very late activation protein 5, alpha subunit; VLA-5

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基因别名: CD49e; FNRA; ITGA5; VLA-5; VLA5; VLA5A

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UniProt ID: (Human) P08648, (Mouse) P11688

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Entrez Gene ID: (Human) 3678, (Mouse) 16402

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功能

virus receptor activity epidermal growth factor receptor binding platelet-derived growth factor receptor binding integrin binding protein binding vascular endothelial growth factor receptor 2 binding metal ion binding cell adhesion molecule binding integrin

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