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Invitrogen
ITGA5 Monoclonal Antibody (5H10.27), PE
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产品信息
A15403
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
5H10.27
抗原
C57BL/6 x A/J F1 mouse mast cell line MC/9 1
偶联物
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
浓度
0.1 mg/mL
纯化类型
purified
保存液
PBS, pH 7.5
内含物
<0.1% sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD49 antigen-like family member E; CD49e; fibronectin receptor alpha polypeptide; Fibronectin receptor subunit alpha; Integrin alpha-5; Integrin alpha-F; VLA-5
基因别名: Cd49e; Fnra; Itga5; VLA5
UniProt ID: (Mouse) P11688
Entrez Gene ID: (Mouse) 16402
cell-substrate junction assembly
cell adhesion
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
leukocyte cell-cell adhesion
integrin-mediated signaling pathway
memory
positive regulation of cell-substrate adhesion
positive regulation of cell migration
cell-substrate adhesion
cell-cell adhesion mediated by integrin
heterotypic cell-cell adhesion
endodermal cell differentiation
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of anoikis
